Sustainable Flourishing

The wanna-be world czar Bill Gates signaled to the world that the climate change hoax jig was up after admitting “The doomsday outlook is causing much of the climate community to focus too much on near-term emissions goals, and it’s diverting resources from the most effective things we should be doing to improve life in a warming world. The biggest problems are poverty and disease, just as they always have been.”

This signals a potential shift in globalist strategy from promising to save the world from human greed and the brown people from the white devil, they’re going to go back to the basics, economic class. President Trump wasn’t letting Gates surrender so gently, however.

He quipped back, “I (WE!) just won the War on the Climate Change Hoax. Bill Gates has finally admitted that he was completely WRONG on the issue,” he added. “It took courage to do so, and for that we are all grateful. MAGA!!!”

Blurb:

President Donald Trump said opponents of the “climate change hoax” had won the struggle after Bill Gates said supporters should pivot their efforts.

Gates has been a longtime proponent of policies to fight climate change, but on Monday he took a far more moderate tone that accepted the survivability of slightly higher global temperatures.

‘Bill Gates has finally admitted that he was completely WRONG on the issue.’

“I (WE!) just won the War on the Climate Change Hoax,” the president wrote on his Truth Social account.

“Bill Gates has finally admitted that he was completely WRONG on the issue,” he added. “It took courage to do so, and for that we are all grateful. MAGA!!!”

Eye Drops: Types, Uses, Potential Risks & Benefits

Eye Drops May One Day Replace Reading Glasses, and Could Help Our Vision as we Age– www.discovermagazine.com
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As we age, we’ll all experience a decline in our vision and will likely need reading glasses. Instead of reaching for those glasses though, imagine taking 2 to 3 eyedrops a day to see something up close.

New research that experts will present at the 43rd Congress of the European Society of Cataract and Refractive Surgeons (ESCRS) explores presbyopia, the condition that makes it hard for the eye to focus on close objects and text, and how eye drops could one day replace eyeglasses.

For this study, lead researcher Giovanna Benozzi, who is also the director of the Center for Advanced Research for Presbyopia in Buenos Aires, Argentina, and her team followed a group of 766 presbyopia patients with an average age of 55 years. The team’s hope was to help find an alternative solution to glasses and eye surgery.

“We conducted this research due to the significant unmet medical need in presbyopia management. Current solutions, such as reading glasses or surgical interventions, have limitations, including inconvenience, social discomfort, and potential risks or complications,” Benozzi said in a press release.

“There is a group of presbyopia patients who have limited options besides spectacles, and who are not candidates for surgery; these are our primary focus of interest,” Bennozi added in the press release.

Graphene - Wikipedia

New graphene oxide super-material is on the way to delivering next-generation supercapacitors, researchers say – Australian Manufacturing Forum
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Australian researchers have identified “a new kind of carbon-based material” allowing supercapacitors to store as much energy as lead-acid batteries while also performing better than conventional batteries at delivering power quickly.

According to a statement from the university on Tuesday, the results are “a major leap forward” for fast, powerful energy storage devices, and are now being commercialised by Ionic Industries.

The new material is named as multiscale reduced graphene oxide (M-rGO) and was created from naturally-occurring graphite. It is described as being made using a “rapid thermal annealing process” and featuring a “highly curved graphene structure with precise pathways for ions to move quickly and efficiently”.

The promising new material is detailed in a new paper in Nature Communications.

Monash’s Professor Mainak Majumder, who was part of the research team and heads the ARC Research Hub for Advanced Manufacturing with 2D Materials (AM2D), said that M-rGO made much more surface area available for storing energy, and which was unlocked by the method of heat treatment.

AI reveals how toughest protein bonds behave– cosmosmagazine.com
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Proteins can form “catch-bonds” that tighten under force, much like a finger trap. Credit: Rafael C. Bernardi, Auburn Physics

Researchers have used artificial intelligence to help uncover how certain protein interactions act like a finger trap, gripping tighter the harder they are pulled.

These interactions, known as catch-bonds, are essential in how the body holds together under stress and how bacteria attach to cells.

The researchers suggest that a better understanding of these bonds could help inform the design of new medications and biomaterials.

Scientists have been unsure as to whether these catch-bonds activate straight away or if they need to be stretched to a certain threshold before they ‘switch on’.

The new study discovered that these bonds activate almost immediately after a force is applied.

Drug shows promise against aggressive cancers in trial– www.futurity.org
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An immunotherapy drug eliminated aggressive cancers in a clinical trial, researchers report.

Over the past 20 years, a class of cancer drugs called CD40 agonist antibodies have shown great promise—and induced great disappointment. While effective at activating the immune system to kill cancer cells in animal models, the drugs had limited impact on patients in clinical trials and caused dangerously systemic inflammatory responses, low platelet counts, and liver toxicity, among other adverse reactions—even at a low dose.

But in 2018, the lab of Rockefeller University’s Jeffrey V. Ravetch demonstrated it could engineer an enhanced CD40 agonist antibody so that it improved its efficacy and could be administered in a manner to limit serious side effects.

The findings came from research on mice, genetically engineered to mimic the pathways relevant in humans. The next step was to have a clinical trial to see the drug’s impact on cancer patients.

Now the results from the phase 1 clinical trial of the drug, dubbed 2141-V11, appear in Cancer Cell. Of 12 patients, six patients saw their tumors shrink, including two who saw them disappear completely.

“Seeing these significant shrinkages and even complete remission in such a small subset of patients is quite remarkable,” says first author Juan Osorio, a visiting assistant professor in Ravetch’s Leonard Wagner Laboratory of Molecular Genetics and Immunology and a medical oncologist at Memorial Sloan Kettering Cancer Center.

 

 

Trauma focused therapy shows promise for children with PTSD– cosmosmagazine.com
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A new study has demonstrated how a specific form of therapy can help improve symptoms in children living with post-traumatic stress disorder (PTSD), a mental health condition that develops after witnessing or experiencing a traumatic event.

Researchers from the University of East Anglia in Norwich, England have examined the effectiveness of trauma-focused cognitive behavioural therapy (CBT) for treating young children who have been subjected to abuse, violence or serious accidents.

CBT is a treatment for mental health conditions that helps individuals to identify any negative thoughts they may have and teaches them self-help strategies to challenge and reduce these unhelpful thought patterns.

According to the World Health Organisation, roughly 3.9% of the world’s population has experienced PTSD at some stage in their life. While trauma-focused CBT is already used to help treat the disorder in adults, children who experience multiple traumas are often considered harder to treat.

“Recent research has shown that more than 7% of young people in the UK will have developed PTSD at some point by the age of 18,” says Richard Meiser-Stedman, the lead researcher of the study from the University of East Anglia, UK.

Best Anti Aging Stem Cell Treatment for Face – Cost, Types and New ...

Scientists test an anti-aging cream that actually works– www.sciencedaily.com
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Against the backdrop of high market demand for effective anti-ageing cosmetics, a team of Chinese researchers assessed the clinical effectiveness of a 0.1 % pterostilbene-containing skincare emulsion against a control emulsion over 28 days with 31 participants.

The study employed a double-blind, split-face design, comparing the left and right sides of the face and using advanced instruments along with subject self-assessments. The set of instruments used, together with the findings, is reported in the team’s published article in the Journal of Dermatologic Science and Cosmetic Technology.

“Our results indicated that the pterostilbene emulsion remarkably improved skin elasticity, firmness, and reduced wrinkles, such as forehead, undereye, and Crow’s feet wrinkles, shares co-author Zhiyuan Chen, Founder of Guangzhou Luanying Cosmetics Co., Ltd. “It also increased the thickness of the epidermis layer, enhanced collagen and elastic fibers, and minimized skin pores.”

Compared to the control emulsion, the pterostilbene emulsion brought about statistically significant improvements, and all subjects expressed higher satisfaction with the pterostilbene emulsion. These results collectively demonstrated the superior anti-aging efficacy of the pterostilbene emulsion through multiple mechanisms.

Will Microbes lead to Quantum Computing Breakthrough?

Quantum computers are here — but why do we need them and what will ...

Scientist returns to microbial roots and discovers potential quantum computing advancement – Phys.org
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To date, his lab at the Yale Microbial Sciences Institute has uncovered the evolutionary trick used by bacteria to breathe through tiny protein filaments, called nanowires, to dispose of excess electrons from the conversion of organic waste to electricity.

The adaptation has enabled bacteria to send electrons over distances 100-times their size through what the scholars refer to as bacterial “snorkeling.”

From its base on Yale’s West Campus, the lab’s previous work revealed the role and atomic structures of the nanowires, but to explain how the electrons were moving so fast, Malvankar found himself returning to where he began—the world of quantum theory.

“Biological theory just couldn’t explain their speed,” explained the associate professor of molecular biophysics and biochemistry. “Either our measurements were wrong, or we needed a new theory.”

3D Bioprinter Could Print “Skin Grafts” for Burn Victims

What are the leading companies in 3D bioprinting Industry?

UP student develops 3D bio-printing alternative to skin grafts – The Witness | Your compass in the community
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Research by a University of Pretoria (UP) PhD graduate has led to the development of a skin replacement product that paves the way for 3D bioprinting of “natural” skin replacement products, offering an alternative to traditional skin grafts.

Dr Hafiza Parkar, a lecturer in UP’s Department of Pharmacology, received her PhD in Pharmacology during UP’s Spring Graduation season in the first week of September.

She said her research is particularly significant for treating secondary intention wounds, which are wounds left open to heal by themselves rather than being stitched together, such as ulcers and burns.

“Creating advanced dermal substitutes that replicate human skin offers a promising solution for treating secondary intention wounds,” Parkar said.

A new blood test could detect Alzheimer’s early

High metabolism is an early sign of Alzheimer's disease ...Alzheimer’s breakthrough: Simple blood test hailed as ‘game-changer’ for diagnosis – Kursiv Media
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A clinical trial in the U.K. is evaluating a new blood test that could reshape how Alzheimer’s disease is diagnosed, according to The National.

Participants showing early signs of dementia are being recruited through NHS memory clinics to evaluate the test’s effectiveness. Researchers expect to have conclusive results within the next three years.

The project, led by University College London, focuses on whether measuring levels of the protein p-tau217 in blood samples can lead to faster and more accurate detection of Alzheimer’s disease. Early studies indicate that the test can identify individuals with cognitive decline with about 80 percent accuracy as being likely to have the disease.

First identified in 1906 by German physician Alois Alzheimer, Alzheimer’s disease is the leading cause of dementia in older adults and is marked by a progressive decline in cognitive abilities.

Alzheimer’s is associated with the accumulation of amyloid and tau proteins in the brain. P-tau217 is considered a particularly strong biomarker because it signals the presence of both.

Scientists just made the first time crystal you can see– www.sciencedaily.com
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Imagine a clock that doesn’t have electricity, but its hands and gears spin on their own for all eternity.

In a new study, physicists at the University of Colorado Boulder have used liquid crystals, the same materials that are in your phone display, to create such a clock — or, at least, as close as humans can get to that idea. The team’s advancement is a new example of a “time crystal.” That’s the name for a curious phase of matter in which the pieces, such as atoms or other particles, exist in constant motion.

The researchers aren’t the first to make a time crystal, but their creation is the first that humans can actually see, which could open a host of technological applications.

“They can be observed directly under a microscope and even, under special conditions, by the naked eye,” said Hanqing Zhao, lead author of the study and a graduate student in the Department of Physics at CU Boulder.

 

Fixing broken bones with a 3D-printing glue gun– cosmosmagazine.com
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A new bone repair solution that could reduce surgery times might soon find its way onto the operating table, with researchers testing out a 3D-printing glue gun on rabbit bone fractures in a new study published in the journal Device.

They showed the glue gun device can print bone grafts directly onto fractures and breaks during surgery by quickly designing the graft on the spot.

Graphical abstract. Credit: Jeon et al. / Device (CC BY-SA)

Bone grafts and implants have historically been made from metal or donor bone, while some recent studies have also used 3D-printed material. When a bone has broken in irregular ways, these implants need to be carefully designed and produced prior to the surgery which can potentially extend waiting and surgery times.

This is not the case for the newly developed device.

Scientists make mind-blowing medical breakthrough using human waste: ‘This can be done easily‘ – The Cool Down

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Researchers have developed engineered yeast that converts human waste into medical-grade material for tooth and bone implants, reported Interesting Engineering.

The development tackles two challenges at once. Untreated human waste threatens waterways by flooding them with excess nutrients. At the same time, demand for biocompatible implant materials continues to grow, with the market expected to hit $3.5 billion by 2030.

Scientists at the University of California, Irvine, and partner institutions have engineered “osteoyeast,” a modified organism that mimics the cells responsible for building bones naturally. The yeast processes urea, adjusting pH levels to trigger calcium and phosphate collection. These minerals crystallize into hydroxyapatite, the same substance found in human bones and teeth.